Gene name:
Corin (Crn;Lrp4) ;
Protein name:
Atrial natriuretic peptide-converting enzyme ;
Alternative:
Low density lipoprotein receptor-related protein 4 ;Corin ;Pro-ANP-converting enzyme ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Serine-type endopeptidase involved in atrial natriuretic peptide hormone processing. Converts through proteolytic cleavage the non-functional propeptide NPPA/ANP into the active hormone which promotes natriuresis, diuresis, and vasodilatation. May also process pro-NPPB the B-type natriuretic peptide.
Subcellular Location:
Cell membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MGRVSFSVRV | SSVRRARCSC | PGRCYLSCRV | PPTTALRALN | GLGCAGVPGE |
100:
TAGGAVGPGP | LGTRGFLSGS | KFQAPGSWKD | CFGAPPAPDV | LRADRSVGEG |
150:
CPQKLVTANL | LRFLLLVLIP | CICALIVLLA | ILLSFVGTLK | RVYFKSNDSE |
200:
PLVTDGEARV | PGVIPVNTVY | YENTGAPSLP | PSQSTPAWTP | RAPSPEDQSH |
250:
RNTSTCMNIT | HSQCQILPYH | STLAPLLPIV | KNMDMEKFLK | FFTYLHRLSC |
300:
YQHILLFGCS | LAFPECVVDG | DDRHGLLPCR | SFCEAAKEGC | ESVLGMVNSS |
350:
WPDSLRCSQF | RDHTETNSSV | RKSCFSLQQE | HGKQSLCGGG | ESFLCTSGLC |
400:
VPKKLQCNGY | NDCDDWSDEA | HCNCSKDLFH | CGTGKCLHYS | LLCDGYDDCG |
450:
DLSDEQNCDC | NLTKEHRCGD | GRCIAAEWVC | DGDHDCVDKS | DEVNCSCHSQ |
500:
GLVECRSGQC | IPSTFQCDGD | EDCKDGSDEE | NCSDSQTPCP | EGEQGCLGSS |
550:
CVESCAGSSL | CDSDSSLSNC | SQCEPITLEL | CMNLPYNHTH | YPNYLGHRTQ |
600:
KEASISWESS | LFPALVQTNC | YKYLMFFACT | ILVPKCDVNT | GQRIPPCRLL |
650:
CEHSKERCES | VLGIVGLQWP | EDTDCNQFPE | ESSDNQTCLL | PNEDVEECSP |
700:
SHFKCRSGRC | VLGSRRCDGQ | ADCDDDSDEE | NCGCKERALW | ECPFNKQCLK |
750:
HTLICDGFPD | CPDSMDEKNC | SFCQDNELEC | ANHECVPRDL | WCDGWVDCSD |
800:
SSDEWGCVTL | SKNGNSSSLL | TVHKSAKEHH | VCADGWRETL | SQLACKQMGL |
850:
GEPSVTKLIP | GQEGQQWLRL | YPNWENLNGS | TLQELLVYRH | SCPSRSEISL |
900:
LCSKQDCGRR | PAARMNKRIL | GGRTSRPGRW | PWQCSLQSEP | SGHICGCVLI |
950:
AKKWVLTVAH | CFEGREDADV | WKVVFGINNL | DHPSGFMQTR | FVKTILLHPR |
1000:
YSRAVVDYDI | SVVELSDDIN | ETSYVRPVCL | PSPEEYLEPD | TYCYITGWGH |
1050:
MGNKMPFKLQ | EGEVRIIPLE | QCQSYFDMKT | ITNRMICAGY | ESGTVDSCMG |
1100:
DSGGPLVCER | PGGQWTLFGL | TSWGSVCFSK | VLGPGVYSNV | SYFVGWIERQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Mouse Atrial natriuretic peptide-converting enzyme
ELISA Kit for Mouse Atrial natriuretic peptide-converting enzyme
ELISA Kit for Mouse Atrial natriuretic peptide-converting enzyme
CLIA Kit for Mouse Atrial natriuretic peptide-converting enzyme
CLIA Kit for Mouse Atrial natriuretic peptide-converting enzyme
CLIA Kit for Mouse Atrial natriuretic peptide-converting enzyme
Polyclonal Antibody for Mouse Atrial natriuretic peptide-converting enzyme
Polyclonal Antibody for Mouse Atrial natriuretic peptide-converting enzyme
Polyclonal Antibody for Mouse Atrial natriuretic peptide-converting enzyme
Monoclonal Antibody for Mouse Atrial natriuretic peptide-converting enzyme
Monoclonal Antibody for Mouse Atrial natriuretic peptide-converting enzyme
Monoclonal Antibody for Mouse Atrial natriuretic peptide-converting enzyme
Protein for Mouse Atrial natriuretic peptide-converting enzyme
Protein for Mouse Atrial natriuretic peptide-converting enzyme
Protein for Mouse Atrial natriuretic peptide-converting enzyme
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6 .
tissue :
Brain .
tissue :
Head .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION
7.
"Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases."
Polzin D.
,
Kaminski H.J.
,
Kastner C.
,
Wang W.
,
Kramer S.
,
Gambaryan S.
,
Russwurm M.
,
Peters H.
,
Wu Q.
,
Vandewalle A.
,
Bachmann S.
,
Theilig F.
Kidney Int.78:650-659(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING (ISOFORMS 1 AND 2)
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION IN W-SH MODEL MICE
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE
11.
"Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy."
Cui Y.
,
Wang W.
,
Dong N.
,
Lou J.
,
Srinivasan D.K.
,
Cheng W.
,
Huang X.
,
Liu M.
,
Fang C.
,
Peng J.
,
Chen S.
,
Wu S.
,
Liu Z.
,
Dong L.
,
Zhou Y.
,
Wu Q.
Nature484:246-250(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE